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PNPLA8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19879

Novus Biologicals, part of Bio-Techne
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NBP2-19879

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rabbit (94%), Rhesus Macaque (98%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for PNPLA8 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human PNPLA8. The exact sequence is proprietary.

Reactivity Notes

Chicken (84%).

Localization

Endoplasmic reticulum membrane; Single-pass membrane protein (By similarity); Golgi apparatus membrane; Single-pass membrane protein (By similarity); Cytoplasm; perinuclear region

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

88 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PNPLA8 Antibody

Western Blot: PNPLA8 Antibody [NBP2-19879]

Western Blot: PNPLA8 Antibody [NBP2-19879]

Western Blot: PNPLA8 Antibody [NBP2-19879] - Sample (30 ug of whole cell lysate) A: Jurkat 7. 5% SDS PAGE gel, diluted at 1:1000.

Applications for PNPLA8 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PNPLA8

Phospholipase A2 catalyzes cleavage of fatty acids from phospholipids, thereby regulating membrane physical properties and the release of lipid second messengers and growth factors. Phospholipase A2 activity also modulates cellular growth programs, inflammation, and ion channel function (Mancuso et al., 2000 [PubMed 10744668]).[supplied by OMIM]

Alternate Names

calcium-independent phospholipase A2-gamma, EC 3.1.1.5, Intracellular membrane-associated calcium-independent phospholipase A2 gamma, iPLA2 gamma, IPLA22, IPLA2-2, iPLA2-gamma, IPLA2GIPLA2(GAMMA), membrane-associated calcium-independent phospholipase A2 gamma, patatin-like phospholipase domain containing 8, Patatin-like phospholipase domain-containing protein 8, PNPLA-gamma

Gene Symbol

PNPLA8

UniProt

Additional PNPLA8 Products

Product Documents for PNPLA8 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PNPLA8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.