PNR/NR2E3 Antibody (2A12)

Novus Biologicals, part of Bio-Techne | Catalog # H00010002-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 2A12

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PNR/NR2E3 Antibodies »

Product Specifications

Immunogen

NR2E3 (AAH41421, 1 a.a. ~ 322 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MCPVDKAHRNQCQACRLKKCLQAGMNQDAVQNERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITAETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPVFSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMETRVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAHHPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN

Reactivity Notes

Human. Other species not tested.

Specificity

NR2E3 - nuclear receptor subfamily 2, group E, member 3

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for PNR/NR2E3 Antibody (2A12)

Western Blot: PNR/NR2E3 Antibody (2A12) [H00010002-M01]

Western Blot: PNR/NR2E3 Antibody (2A12) [H00010002-M01]

Western Blot: PNR/NR2E3 Antibody (2A12) [H00010002-M01] - Analysis of NR2E3 expression in transfected 293T cell line by NR2E3 monoclonal antibody (M01), clone 2A12.Lane 1: NR2E3 transfected lysate(44.7 KDa).Lane 2: Non-transfected lysate.
Sandwich ELISA: PNR/NR2E3 Antibody (2A12) [H00010002-M01] - Detection limit for recombinant GST tagged NR2E3 is approximately 0.3ng/ml as a capture antibody.

Applications for PNR/NR2E3 Antibody (2A12)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against recombinant protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PNR/NR2E3

This protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand-dependent transcription factor. Defects in this gene are a cause of enhanced S cone syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified.

Long Name

Photoreceptor-specific Nuclear Receptor

Alternate Names

NR2E3, RNR

Entrez Gene IDs

10002 (Human)

Gene Symbol

NR2E3

OMIM

268000 (Human)

UniProt

AAH41421 (Human)

Additional PNR/NR2E3 Products

Product Documents for PNR/NR2E3 Antibody (2A12)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PNR/NR2E3 Antibody (2A12)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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