Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3D4

Concentration

1 mg/ml

View all PNR/NR2E3 Antibodies »

Product Summary for PNR/NR2E3 Antibody (OTI3D4)

Immunogen

Full length human recombinant protein of human NR2E3 (NP_057430) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

39.5 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PNR/NR2E3 Antibody (OTI3D4)

Western Blot: PNR/NR2E3 Antibody (OTI3D4) [NBP2-46235]

Western Blot: PNR/NR2E3 Antibody (OTI3D4) [NBP2-46235]

Western Blot: PNR/NR2E3 Antibody (3D4) [NBP2-46235] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY NR2E3.

Applications for PNR/NR2E3 Antibody (OTI3D4)

Application
Recommended Usage

Western Blot

1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PNR/NR2E3

Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Long Name

Photoreceptor-specific Nuclear Receptor

Alternate Names

NR2E3, RNR

Gene Symbol

NR2E3

Additional PNR/NR2E3 Products

Product Documents for PNR/NR2E3 Antibody (OTI3D4)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PNR/NR2E3 Antibody (OTI3D4)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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