PNR/NR2E3 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS5770

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Porcine, Bat, Bovine, Equine, Hamster

Predicted:

Chimpanzee (100%), Monkey (100%), Primate (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all PNR/NR2E3 Antibodies »

Product Specifications

Immunogen

Synthetic 19 amino acid peptide from ligand-binding domain of human PNR/NR2E3.

Epitope

Ligand-binding domain

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (95%).

Specificity

Human NR2E3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for PNR/NR2E3 Antibody - BSA Free

Immunohistochemistry-Paraffin: PNR/NR2E3 Antibody - BSA Free [NLS5770]

Immunohistochemistry-Paraffin: PNR/NR2E3 Antibody - BSA Free [NLS5770]

Immunohistochemistry-Paraffin: PNR/NR2E3 Antibody [NLS5770] - Analysis of anti-NR2E3 antibody with human retina at 30 ug/ml.

Applications for PNR/NR2E3 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

30 ug/ml
Application Notes
.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: PNR/NR2E3

Photoreceptor-specific nuclear receptor (PNR), a NR2 Hepatocyte NF4-Like Receptor, has been suggested to affect cone cell proliferation in eye development. It has been shown to have a role in determining photoreceptor phenotype during human retinogenesis. In RD7 mice, a deletion in PNR results in hereditary retinal dysplasia and degeneration. A homozygous missense mutation in PNR has been linked to retinitis pigmentosa in Crypto-Jews of Belmonte. Two alternatively spliced isoforms have been documented. PNR is expressed in the retina. ESTs have been isolated from cancerous human lung, colon, and ovary, and from normal human eye.

Long Name

Photoreceptor-specific Nuclear Receptor

Alternate Names

NR2E3, RNR

Entrez Gene IDs

10002 (Human)

Gene Symbol

NR2E3

UniProt

Q9Y5X4 (Human)

Additional PNR/NR2E3 Products

Product Documents for PNR/NR2E3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for PNR/NR2E3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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