Podocin/NPHS2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-26057

Novus Biologicals, part of Bio-Techne
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NBP2-26057
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Bovine (100%), Porcine (100%). Backed by our 100% Guarantee.

Applications

Validated:

Peptide ELISA, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Podocin/NPHS2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-SPSKPVEPLNPKK corresponding to C-Terminus according to NP_055440.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Podocin/NPHS2 Antibody

Western Blot: Podocin/NPHS2 Antibody [NBP2-26057]

Western Blot: Podocin/NPHS2 Antibody [NBP2-26057]

Western Blot: Podocin/NPHS2 Antibody [NBP2-26057] - Staining of Human (A) and Mouse (B) Kidney lysate with antibody at 1 ug/mL (35 ug protein in RIPA buffer). Detected by chemiluminescence.

Applications for Podocin/NPHS2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:64000

Western Blot

0.5 - 2 ug/mL
Application Notes
WB: Approx 42-45 kDa band observed in Human and Mouse Kidney lysates (calculated MW of 42.2 kDa according to Human NP_055440.1 and Mouse NP_569723.1)

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Podocin/NPHS2

NPHS2 encodes the glomerular protein podocin which plays a role in the regulation of glomerular permeability, and acts as a linker between the plasma membrane and the cytoskeleton. Defects in this gene are the cause of autosomal recessive steroid-resistant nephrotic syndrome (SRN). SRN is characterized by onset between three months and five years, resistance to steroid therapy and rapid progression to end-stage renal disease. An alternative splice variant has been described but its full length sequence has not been determined. [provided by RefSeq]

Alternate Names

Nephrosis 2, NPHS2, PDCN, SRN1

Entrez Gene IDs

7827 (Human)

Gene Symbol

NPHS2

Additional Podocin/NPHS2 Products

Product Documents for Podocin/NPHS2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Podocin/NPHS2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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