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POLN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58780

Novus Biologicals, part of Bio-Techne
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NBP2-58780
NBP2-58780-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: WQLFRTLELPLIPILAVMESHAIQVNKEEMEKTSALLGARLKELEQEAHFVAGERFLITSNNQLREILFGKLKLHLLSQRNSLPRTGLQK

Reactivity Notes

Mouse 88%, Rat 84%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for POLN Antibody

Immunocytochemistry/ Immunofluorescence: POLN Antibody [NBP2-58780]

Immunocytochemistry/ Immunofluorescence: POLN Antibody [NBP2-58780]

Immunocytochemistry/Immunofluorescence: POLN Antibody [NBP2-58780] - Staining of human cell line RH-30 shows localization to nucleoplasm.

Applications for POLN Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: POLN

POLN, also known as DNA polymerase nu, is localized to the nucleus and highly expressed in the heart and testis. Current research on POLN is being performed in relation to several diseases and disorders including Fanconi anemia, pneumonia, and tuberculosis. POLN has also been shown to have interactions with PCNA, FANCA, FANCG, FANCD2, and RAD51 in the DNA replication and DNA repair pathways.

Alternate Names

DNA polymerase N, DNA polymerase nu, DNA polymerase POL4P, EC 2.7.7.7, POL4P, polymerase (DNA directed) nu

Gene Symbol

POLN

Additional POLN Products

Product Documents for POLN Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for POLN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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