Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Western Blot

Label

Janelia Fluor 585

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # PKS161f/B7

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Polycystin-1/PKD1 Antibodies »

Product Specifications

Immunogen

Recombinant protein (233 aa)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Polycystin-1/PKD1 Antibody (PKS161f/B7) [Janelia Fluor® 585]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Polycystin-1/PKD1

Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes including conventional (c) PKC isoforms (alpha, betaI, betaII and gamma) and novel (n) PKC isoforms (delta, episilon , zeta, eta and theta). Patterns of expression for each PKC isoform differs among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of nPKC delta and episilon are independent of Ca++. On the other hand, nPKC delta and episilon, as well as all of the cPKC members, possess phorbol ester-binding activities and kinase activities.

Alternate Names

Pc-1, PKD1, Polycystin1, TRPP1

Gene Symbol

PKD1

Additional Polycystin-1/PKD1 Products

Product Documents for Polycystin-1/PKD1 Antibody (PKS161f/B7) [Janelia Fluor® 585]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Polycystin-1/PKD1 Antibody (PKS161f/B7) [Janelia Fluor® 585]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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