Polycystin 2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-51975

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Polycystin 2 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-ERAKLKRREVLGR corresponding to internal region according to NP_000288.1.

Epitope

C-ERAKLKRREVLGR

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Polycystin 2 Antibody

Western Blot: Polycystin 2 Antibody [NBP1-51975]

Western Blot: Polycystin 2 Antibody [NBP1-51975]

Western Blot: Polycystin 2 Antibody [NBP1-51975] - (1ug/ml) staining of HeLa lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Polycystin 2 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:2000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 100 kDa band observed in HeLa lysate (calculated MW of 110 kDa band according to NP_000288.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Polycystin 2

FUNCTION: Functions as a calcium permeable cation channel. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. SUBUNIT: Interacts with PKD1. PKD1 requires the presence of PKD2 for stable expression. Interacts with CD2AP. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed in mesenchymally derived structures in the developing embryo at day 12.5. In adult, mostly expressed in kidney.

Alternate Names

APKD2, Autosomal dominant polycystic kidney disease type II protein, MGC138466, MGC138468, PC2, Pc-2, PKD4, polycystic kidney disease 2 (autosomal dominant), Polycystic kidney disease 2 protein, polycystin-2, polycystwin, R48321, transient receptor potential cation channel, subfamily P, member 2, TRPP2

Entrez Gene IDs

5311 (Human); 18764 (Mouse); 498328 (Rat)

Gene Symbol

PKD2

UniProt

NP_000288.1 (Human)

Additional Polycystin 2 Products

Product Documents for Polycystin 2 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Polycystin 2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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