Polypeptide GalNac Transferase 3/GALNT3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81849

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-81849
NBP1-81849-25ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Polypeptide GalNAc Transferase 3/GALNT3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EESRMERNMKNKNKMLDLMLEAVNNIKDAMPKMQIGAPVRQNIDAGERPCLQGYYTAAELKPVLDRPPQDSNAPGASGKAFKTTNLSVEEQKEKERGEAKHC

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (86%), Rat (87%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Polypeptide GalNac Transferase 3/GALNT3 Antibody

Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849]

Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849]

Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849] - Staining in human stomach and lymph node tissues using anti-GALNT3 antibody. Corresponding GALNT3 RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849]

Immunocytochemistry/ Immunofluorescence: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849]

Immunocytochemistry/Immunofluorescence: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849] - Staining of human cell line A-431 shows localization to the Golgi apparatus. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849]

Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849]

Immunohistochemistry-Paraffin: Polypeptide GalNac Transferase 3/GALNT3 Antibody [NBP1-81849] - Staining of human lymph node shows low expression as expected.
View 1 more images

Applications for Polypeptide GalNac Transferase 3/GALNT3 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Polypeptide GalNAc Transferase 3/GALNT3

GALNT3, also known as Polypeptide N-acetylgalactosaminyltransferase 3, has a 633 amino acid long isoform that is 73 kDa and a short 192 amino acid isoform that is 22 kDa; is located in the Golgi apparatus; plays a central role in phosphate homeostasis; acts as a catalyzer in the initiation of O-linked oligosaccharide biosynthesis, and the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor; shows an activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5; and glycosylates FGF23, and probably fibronectin in vivo too. Studies on this protein have shown a relationship with the following diseases and disorders: tumoral calcinosis, hyperphosphatemic calcinosis, hyperostosis-hyperphosphatemia syndrome, hyperphosphatemic familial tunoral calcinisis, normophosphatemic familial tumoral calcinosis, testicular microlithiasis, bile duct carcinoma, periostitis, squamous cell carcinoma, diabetes mellitus, colon adenocarcinoma, lung adenocarcinoma, pancreatic cancer, metabolic disorders, and lung cancer. This protein has also been shown to have interactions with CIGALT1, CIGALT1C1, ST6GALNAC1, B3GNT6, and GCNT1 in pathways such as O-linked glycosylation of mucins, metabolism of proteins, and post-translational protein modification.

Long Name

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3

Alternate Names

GalNAc-T3, HFTC, HHS, pp-GaNTase 3

Gene Symbol

GALNT3

Additional Polypeptide GalNAc Transferase 3/GALNT3 Products

Product Documents for Polypeptide GalNac Transferase 3/GALNT3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Polypeptide GalNac Transferase 3/GALNT3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.