POMC Antibody (6D2B5) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61793

Novus Biologicals, part of Bio-Techne
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NBP2-61793
NBP2-61793-0.025ml
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 6D2B5

Format

BSA Free

Concentration

1 mg/ml

View all POMC Antibodies »

Product Specifications

Immunogen

Purified recombinant fragment of human POMC (AA: 1-150) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

29.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for POMC Antibody (6D2B5) - BSA Free

Western Blot: POMC Antibody (6D2B5)BSA Free [NBP2-61793]

Western Blot: POMC Antibody (6D2B5)BSA Free [NBP2-61793]

Western Blot: POMC Antibody (6D2B5) [NBP2-61793] - Analysis using POMC mAb against human POMC (AA: 1-150) recombinant protein. (Expected MW is 41.9 kDa)
Immunocytochemistry/ Immunofluorescence: POMC Antibody (6D2B5) - BSA Free [NBP2-61793]

Immunocytochemistry/ Immunofluorescence: POMC Antibody (6D2B5) - BSA Free [NBP2-61793]

Immunocytochemistry/Immunofluorescence: POMC Antibody (6D2B5) [NBP2-61793] - Analysis of Hela cells using POMC mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor- 555 phalloidin. Goat anti-Mouse IgG (H+L) DyLight 488 secondary antibody was used.
Western Blot: POMC Antibody (6D2B5)BSA Free [NBP2-61793]

Western Blot: POMC Antibody (6D2B5)BSA Free [NBP2-61793]

Western Blot: POMC Antibody (6D2B5) [NBP2-61793] - Analysis using POMC mAb against HEK293 (1) and POMC (AA: 1-150)-hIgGFc transfected HEK293 (2) cell lysate.
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Applications for POMC Antibody (6D2B5) - BSA Free

Application
Recommended Usage

ELISA

1:10000

Immunocytochemistry/ Immunofluorescence

1:200-1:1000

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: POMC

This gene encodes a preproprotein that undergoes extensive, tissue-specific, post-translational processing via cleavage by subtilisin-like enzymes known as prohormone convertases. There are eight potential cleavage sites within the preproprotein and, depending on tissue type and the available convertases, processing may yield as many as ten biologically active peptides involved in diverse cellular functions. The encoded protein is synthesized mainly in corticotroph cells of the anterior pituitary where four cleavage sites are used; adrenocorticotrophin, essential for normal steroidogenesis and the maintenance of normal adrenal weight, and lipotropin beta are the major end products. In other tissues, including the hypothalamus, placenta, and epithelium, all cleavage sites may be used, giving rise to peptides with roles in pain and energy homeostasis, melanocyte stimulation, and immune modulation. These include several distinct melanotropins, lipotropins, and endorphins that are contained within the adrenocorticotrophin and beta-lipotropin peptides. The antimicrobial melanotropin alpha peptide exhibits antibacterial and antifungal activity. Mutations in this gene have been associated with early onset obesity, adrenal insufficiency, and red hair pigmentation. Alternatively spliced transcript variants encoding the same protein have been described.;

Long Name

Proopiomelanocortin

Alternate Names

ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte-stimulating hormone, alpha-MSH, beta-endorphin, beta-LPH, beta-melanocyte-stimulating hormone, beta-MSH, CLIP, corticotropin-like intermediary peptide, Corticotropin-lipotropin, gamma-LPH, gamma-MSH, lipotropin beta, lipotropin gamma, LPH, melanotropin alpha, melanotropin beta, melanotropin gamma, met-enkephalin, MSH, NPP, POC, pro-ACTH-endorphin, proopiomelanocortin, pro-opiomelanocortin, proopiomelanocortin preproprotein

Gene Symbol

POMC

Additional POMC Products

Product Documents for POMC Antibody (6D2B5) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for POMC Antibody (6D2B5) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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