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POMT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19891

Novus Biologicals, part of Bio-Techne
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NBP2-19891

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (99%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human POMT1. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (99%), Mouse (80%), Bovine (85%).

Localization

Endoplasmic reticulum membrane; Multi-pass membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

85 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for POMT1 Antibody

POMT1 Antibody

Western Blot: POMT1 Antibody [NBP2-19891] -

Western Blot: POMT1 Antibody [NBP2-19891] - Whole cell extract (30 ug) was separated by 7.5% SDS-PAGE, and the membrane was blotted with POMT1 antibody [C1C3] (NBP2-19891) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.

Applications for POMT1 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: POMT1

The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT2 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS) and limb-girdle muscular dystrophy type 2K (LGMD2K). Several transcript variants encoding different isoforms have been found for this gene.

Alternate Names

Dolichyl-phosphate-mannose--protein mannosyltransferase 1, EC 2.4.1, EC 2.4.1.109, FLJ37239, LGMD2K, MDDGA1, MDDGB1, MDDGC1, protein O-mannosyl-transferase 1, protein-O-mannosyltransferase 1, RT

Gene Symbol

POMT1

UniProt

Additional POMT1 Products

Product Documents for POMT1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for POMT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.