Porimin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-68797

Novus Biologicals, part of Bio-Techne
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NBP2-68797
NBP2-68797-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Porimin Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: ANIENSGLPHNSSANSTETLQHVPSDHTNETSNSTVKPPTSVASDSSNTTVTTMKPTA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Porimin Antibody

Immunocytochemistry/ Immunofluorescence: Porimin Antibody [NBP2-68797]

Immunocytochemistry/ Immunofluorescence: Porimin Antibody [NBP2-68797]

Immunocytochemistry/Immunofluorescence: Porimin Antibody [NBP2-68797] - Staining of human cell line RH-30 shows localization to the Golgi apparatus & vesicles.

Applications for Porimin Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation/Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Porimin

Porimin was identified by a monoclonal antibody developed by immunizing mice with apoptotic cells. One of these antibodies, designated anti-Porimin (for pro-oncosis receptor inducing membrane injury), was found to directly induce a unique type of cell death in Jurkat cells by binding to a 110-kDa cell surface receptor on Jurkat cells. Anti-Porimin-mediated cell death was preceded by cell aggregation, formation of plasma membrane pores, and the appearance of membrane blebs. More important, these cells show neither DNA fragmentation nor apoptotic bodies, but display lethal damage of the cell membrane.

Long Name

Pro-Oncosis Receptor Inducing Membrane Injury

Alternate Names

KCT3, TMEM123

Gene Symbol

TMEM123

Additional Porimin Products

Product Documents for Porimin Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Porimin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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