POT1 Antibody [DyLight 755]

Novus Biologicals, part of Bio-Techne | Catalog # NB500-176IR

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Product Datasheet / COA / SDS

View Available Conjugates

Conjugate

Catalog #

Unconjugated

NB500-176

Alexa Fluor 350

NB500-176AF350

Alexa Fluor 405

NB500-176AF405

Alexa Fluor 488

NB500-176AF488

Alexa Fluor 532

NB500-176AF532

Alexa Fluor 594

NB500-176AF594

Alexa Fluor 647

NB500-176AF647

Alexa Fluor 700

NB500-176AF700

Alexa Fluor 750

NB500-176AF750

Allophycocyanin

NB500-176APC

Biotin

NB500-176B

CoraFluor 1

NB500-176CL1

DyLight 350

NB500-176UV

DyLight 405

NB500-176V

DyLight 488

NB500-176G

DyLight 550

NB500-176R

DyLight 594

NB500-176DL594

DyLight 650

NB500-176C

DyLight 680

NB500-176FR

HRP

NB500-176H

Janelia Fluor 525

NB500-176JF525

Janelia Fluor 549

NB500-176JF549

Janelia Fluor 646

NB500-176JF646

Janelia Fluor 669

NB500-176JF669

mFluor Violet 450 SE

NB500-176MFV450

mFluor Violet 500 SE

NB500-176MFV500

mFluor Violet 610 SE

NB500-176MFV610

PE

NB500-176PE

PerCP

NB500-176PCP

Product Specifications
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (95%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

DyLight 755 (Excitation = 754 nm, Emission = 776 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all POT1 Antibodies »

Product Specifications

Immunogen

A synthetic peptide made to an internal portion of the human POT1 protein sequence (between residues 200-300). [UniProt# Q9NUX5]

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: monkey (95%), rat (82%), and mouse (72%).

Localization

Nuclear

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for POT1 Antibody [DyLight 755]

Application

Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: POT1

POT1 (protection of telomeres 1), a telomere regulator, is a single-stranded telomeric DNA-binding protein that controls telomerase-mediated telomere elongation. Telomere maintenance is required for protection against changes in telomere length, which has been implicated in ageing and certain cancers. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Excessive transcriptional expression of POT1 has been associated with stomach cancers.

Long Name

Protection of Telomeres Protein 1

Alternate Names

DKFZp586D211, HPOT1, POT1 protection of telomeres 1 homolog, POT1-like telomere end-binding protein, protection of telomeres 1 homolog (S. pombe), protection of telomeres protein 1

Gene Symbol

POT1

Additional POT1 Products

Product Documents for POT1 Antibody [DyLight 755]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for POT1 Antibody [DyLight 755]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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