PPAP2C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-11903

Novus Biologicals, part of Bio-Techne
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NBP3-11903-100ug
NBP3-11903-25ug
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PPAP2C Antibodies »

Product Specifications

Immunogen

Unique peptide derived from the human lysophospholipid phosphatase 2 protein. (Uniprot: O43688)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PPAP2C Antibody

Western Blot: PPAP2C Antibody [NBP3-11903]

Western Blot: PPAP2C Antibody [NBP3-11903]

Western Blot: PPAP2C Antibody [NBP3-11903] - Western blot analysis using PPAP2C antibody on vector-controlled HEK-293 cells (V) and HEK-293 cells overexpressing LPP2 protein (2) at 1 ug/ml

Applications for PPAP2C Antibody

Application
Recommended Usage

Western Blot

10 - 15 ug/ml
Application Notes
This antibody can be used for Western blotting (10-15 ug/ml). NOTE: Boiling LPP2 with sample buffer will aggregate the protein. Lysates should be prepared by mixing cells with lysis buffer (possibly with extra detergent) to solubilize the protein before adding sample buffer and lysate SHOULD NOT be boiled/heated..

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

PBS

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PPAP2C

PPAP2C, also referred to as Phosphatidic Acid Phosphatase Type 2C, has a canonical sequence that is 288 amino acids long and approximately 32kDa, and two other isoforms that are 309 and 232 amino acids in length, respectively. PPAP2C is an enzyme that hydrolyzes S1P, C1P and LPA, and catalyzes the conversion of phosphatidic acid to diacylglycerol. Current research surrounding PPAP2C has shown a possible linkage with strabismus and gastroenteritis. PPAP2C has also been shown to interact with APLP1, BAG6, GALC, MLH1, and UNC119 in pathways such as triacylglyceride synthesis, sphingolipid metabolism, triacylglycerol biosynthesis, and Fc gamma R-mediated phagocytosis.

Alternate Names

EC 3.1.3.4, LPP2PAP2-g, PAP2c, PAP-2clipid phosphate phosphohydrolase 2, PAP2-G, PAP2-gamma, Phosphatidate phosphohydrolase type 2c, Phosphatidic acid phosphatase 2c, phosphatidic acid phosphatase type 2C, phosphatidic acid phosphohydrolase type 2c, type-2 phosphatidic acid phosphatase-gamma

Gene Symbol

PLPP2

UniProt

O43688 (Human)

Additional PPAP2C Products

Product Documents for PPAP2C Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPAP2C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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