Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all PPAPDC3 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 19 amino acid synthetic peptide from near the amino of terminus human PPAPDC3. The immunogen is located within the first 50 amino acids of PPAPDC3. Amino Acid Squence: PPKGGPEPRSSGRKASGPS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PPAPDC3 Antibody - BSA Free

Western Blot: PPAPDC3 AntibodyBSA Free [NBP1-76246]

Western Blot: PPAPDC3 AntibodyBSA Free [NBP1-76246]

Western Blot: PPAPDC3 Antibody [NBP1-76246] - Mouse heart tissue lysate with PPAPDC3 antibody at (A) 1 and (B) 2 ug/mL.
PPAPDC3 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: PPAPDC3 Antibody - BSA Free [NBP1-76246] -

Immunocytochemistry/ Immunofluorescence: PPAPDC3 Antibody - BSA Free [NBP1-76246] - Immunofluorescence of PPAPDC3 in mouse heart tissue with PPAPDC3 antibody at 20 u/mL.

Applications for PPAPDC3 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PPAPDC3

PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.

Alternate Names

C9orf67, chromosome 9 open reading frame 67, EC 3.1.3, EC 3.1.3.-, FLJ14662, KIAA0515, MGC12921, NET39, phosphatidic acid phosphatase type 2 domain containing 3, Phosphatidic acid phosphatase type 2 domain-containing protein 3, probable lipid phosphate phosphatase PPAPDC3

Gene Symbol

PLPP7

UniProt

EAW87966 (Human)

Additional PPAPDC3 Products

Product Documents for PPAPDC3 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPAPDC3 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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