PPFIA3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-30453

Novus Biologicals, part of Bio-Techne
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NBP2-30453
NBP2-30453-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%), Rat (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPFIA3 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SSGHSTPRLAPPSPAREGTDKANHVPKEEAGAPRGEGPAIPGDTPPPTPRSARLERMTQALALQAGSLEDG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PPFIA3 Antibody

Immunohistochemistry-Paraffin: PPFIA3 Antibody [NBP2-30453]

Immunohistochemistry-Paraffin: PPFIA3 Antibody [NBP2-30453]

Immunohistochemistry-Paraffin: PPFIA3 Antibody [NBP2-30453] - Staining of human liver shows low expression as expected.
Immunohistochemistry: PPFIA3 Antibody [NBP2-30453]

Immunohistochemistry: PPFIA3 Antibody [NBP2-30453]

Immunohistochemistry: PPFIA3 Antibody [NBP2-30453] - Immunohistochemical staining of human lateral ventricle shows moderate cytoplasmic positivity in neuronal cells.
Immunohistochemistry-Paraffin: PPFIA3 Antibody [NBP2-30453]

Immunohistochemistry-Paraffin: PPFIA3 Antibody [NBP2-30453]

Immunohistochemistry-Paraffin: PPFIA3 Antibody [NBP2-30453] - Staining of human cerebral cortex shows high expression.
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Applications for PPFIA3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PPFIA3

PPFIA3, also known as Liprin-alpha-3, has a 1,194 amino acid long isoform that is 133kDa and a slightly shorter 1,185 amino acid isoform that is approximately 132kDa. PPFIA3 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. PPFIA3 is localized to the cytoplasm and cell surface, and is highly expressed in the brain. As a member of the Liprin family, research shows that PPFIA3 may play a role in the disassembly of focal adhesions. Current research surrounding PPFIA3 shows that it may be implicated in various diseases and disorders including cerebritis, cerebral malformations, cocaine abuse, neuronitis and epilepsy. PPFIA3 has also been shown to interact with GIT1, PTPRS, PIK3R1, ERC2, and PPFIBP2.

Alternate Names

KIAA0654liprin, liprin-alpha-3, LPNA3liprin-alpha 3, MGC126567, MGC126569, Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-3, protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 3, protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3, PTPRF-interacting protein alpha-3

Gene Symbol

PPFIA3

UniProt

O75145 (Human)

Additional PPFIA3 Products

Product Documents for PPFIA3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPFIA3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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