PPOX Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-79615

Novus Biologicals, part of Bio-Techne
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NBP1-79615
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all PPOX Antibodies »

Product Specifications

Immunogen

Synthetic peptide directed towards the N terminal of human PPOXThe immunogen for this antibody is PPOX. Peptide sequence SSERLGGWIRSVRGPNGAIFELGPRGIRPAGALGARTLLLVSELGLDSEV. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for PPOX Antibody

Western Blot: PPOX Antibody [NBP1-79615]

Western Blot: PPOX Antibody [NBP1-79615]

Western Blot: PPOX Antibody [NBP1-79615] - Titration: 0.2-1 ug/ml, Positive Control: HT1080 cell lysate.

Applications for PPOX Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PPOX

PPOX encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

Alternate Names

EC 1.3.3.4, MGC8485, PPOVP, protoporphyrinogen oxidase, V290M, variegate porphyria

Gene Symbol

PPOX

UniProt

NP_000300 (Human)

Additional PPOX Products

Product Documents for PPOX Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPOX Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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