PPOX Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19905

Novus Biologicals, part of Bio-Techne
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NBP2-19905
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (90%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPOX Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human PPOX. The exact sequence is proprietary.

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (81%).

Localization

Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

51 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PPOX Antibody

Western Blot: PPOX Antibody [NBP2-19905]

Western Blot: PPOX Antibody [NBP2-19905]

Western Blot: PPOX Antibody [NBP2-19905] - Sample (30 ug of whole cell lysate) A: A549 B: HCT116 10% SDS PAGE gel, diluted at 1:2000.

Applications for PPOX Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PPOX

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq]

Alternate Names

EC 1.3.3.4, MGC8485, PPOVP, protoporphyrinogen oxidase, V290M, variegate porphyria

Gene Symbol

PPOX

UniProt

P50336 (Human)

Additional PPOX Products

Product Documents for PPOX Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PPOX Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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