PPP2CB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00005516-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPP2CB Antibodies »

Product Specifications

Immunogen

PPP2CB (AAH12022, 1 a.a. - 309 a.a.) full-length human protein. MDDKAFTKELDQWVEQLNECKQLNENQVRTLCEKAKEILTKESNVQEVRCPVTVCGDVHGQFHDLMELFRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYPERITILRGNHESRQITQVYGFYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDTLDHIRALDRLQEVPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNHANGLTLVSRAHQLVMEGYNWCHDRNVVTIFSAPNYCYRCGNQAAIMELDDTLKYSFLQFDPAPRRGEPHVTRRTPDYFL

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for PPP2CB Antibody

Western Blot: PPP2CB Antibody [H00005516-B01P]

Western Blot: PPP2CB Antibody [H00005516-B01P]

Western Blot: PPP2CB Antibody [H00005516-B01P] - Analysis of PPP2CB expression in transfected 293T cell line by PPP2CB polyclonal antibody. Lane 1: PPP2CB transfected lysate(34.1 KDa). Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: PPP2CB Antibody [H00005516-B01P]

Immunocytochemistry/ Immunofluorescence: PPP2CB Antibody [H00005516-B01P]

Immunocytochemistry/Immunofluorescence: PPP2CB Antibody [H00005516-B01P] - Analysis of purified antibody to PPP2CB on HeLa cell. (antibody concentration 10 ug/ml)

Applications for PPP2CB Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
It has been used for WB and Functional.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PPP2CB

PPP2CB also known as Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform, is a 309 amino acid protein that is 36 kDa, localizes in cytoplasm and nucleus, is implicated in the negative control of cell growth and division and modulates the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Studies of this protein are being done on the following diseases and disorders: cerebral cavernous malformations, cavernous malformation, cerebral cavernous malformations 3, Werner syndrome, Chagas disease, hepatitis c, trypanosomiasis, cerebritis, Alzheimer's disease, prostate cancer, hepatitis, prostatitis, immunodeficiency, malaria, neuronitis, and breast cancer. PPP2CB protein has been linked to Neurophysiological process Glutamate regulation of Dopamine D1A receptor signaling, Signal transduction Calcium signaling, Development Beta-adrenergic receptors signaling via cAMP,Cell cycle Regulation of G1/S transition (part 1), Cell cycle Start of DNA replication in early S phase, Cell Cycle Control by BTG Proteins, CDK5 Pathway, mTOR Pathway, AMPK Enzyme Complex Pathway, Cyclins and Cell Cycle Regulation, Akt Pathway, Insulin Pathway, TGF-beta Pathway, Wnt Pathway, Apoptosis and survival BAD phosphorylation, and many other pathways where interacts with HIST1H4B , HIST1H4A, HIST1H4C, HIST1H4D, HIST1H4E, AXIN2, and over 280 other interacting proteins.

Alternate Names

EC 3.1.3.16, PP2Abeta, PP2A-beta, PP2CB, protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform, protein phosphatase 2, catalytic subunit, beta isoform, protein phosphatase 2, catalytic subunit, beta isozyme, protein phosphatase 2A catalytic subunit, beta isoform, protein phosphatase type 2A catalytic subunit, serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform, serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

Gene Symbol

PPP2CB

UniProt

AAH12022 (Human)

Additional PPP2CB Products

Product Documents for PPP2CB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PPP2CB Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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