PPP4R2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-19915

Novus Biologicals, part of Bio-Techne
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NBP2-19915
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PPP4R2 Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human PPP4R2. The exact sequence is proprietary.

Localization

Centrosome

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PPP4R2 Antibody

Western Blot: PPP4R2 Antibody [NBP2-19915]

Western Blot: PPP4R2 Antibody [NBP2-19915]

Western Blot: PPP4R2 Antibody [NBP2-19915] - Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates B: PPP4R2 transfected 293T lysate 10% SDS PAGE gel, diluted at 1:5000.
Western Blot: PPP4R2 Antibody [NBP2-19915]

Western Blot: PPP4R2 Antibody [NBP2-19915]

Western Blot: PPP4R2 Antibody [NBP2-19915] - Sample (30 ug of whole cell lysate) A: A431 B: Jurkat 10% SDS PAGE gel, diluted at 1:1000.

Applications for PPP4R2 Antibody

Application
Recommended Usage

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol, 1% BSA

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PPP4R2

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.

Alternate Names

MGC131930, PP4R2, protein phosphatase 4, regulatory subunit 2, serine/threonine-protein phosphatase 4 regulatory subunit 2

Gene Symbol

PPP4R2

Additional PPP4R2 Products

Product Documents for PPP4R2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PPP4R2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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