preproANP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14872

Novus Biologicals, part of Bio-Techne
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NBP2-14872
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Squirrel, Xenopus

Cited:

Mouse

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all preproANP Antibodies »

Product Specifications

Immunogen

Full length human preproANP Recombinant protein.

Reactivity Notes

Frog (100%), Canine (83%), Porcine (87%), Rabbit (81%), Bovine (83%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

17 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for preproANP Antibody

Western Blot: preproANP Antibody [NBP2-14872]

Western Blot: preproANP Antibody [NBP2-14872]

Western Blot: preproANP Antibody [NBP2-14872] - Expression of cardiac hypertrophic biomarkers in cultured neonatal cardiomyocytes. Secretory preproANP was detected via immunoblot analyses of culture media collected at indicated time points and normalized to total protein measured by Coomassie staining (n = 4 mice). Pictured are representative scans of the preproANP immunoblot and corresponding Coomassie staining. Image collected and cropped by CiteAb from the following publication (//pubmed.ncbi.nlm.nih.gov/32377307/) licensed under a CC-BY license.
Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-14872]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-14872]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-14872] - Rat heart. ANP stained by preproANP antibody diluted at 1:500. Antigen Retrieval: Citrate buffer, pH 6.0, 15 min
Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-14872]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-14872]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-14872] - Human ovarian carcinoma. preproANP antibody dilution: 1:250. Antigen Retrieval: Trilogy(TM) (EDTA based, pH 8.0) buffer, 15min.
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Applications for preproANP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Assay dependent

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:1000-1:10000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: preproANP

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

Alternate Names

ANF, ANP, ATFB6, atrial natriuretic factor prohormone, atrial natriuretic peptide prohormone, ATRST2, CDD, CDD-ANF, CDP, natriuretic peptides A, PND

Gene Symbol

NPPA

Additional preproANP Products

Product Documents for preproANP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for preproANP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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