preproANP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-34105

Novus Biologicals, part of Bio-Techne
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NBP2-34105
NBP2-34105-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all preproANP Antibodies »

Product Specifications

Immunogen

This antibody was developed against recombinant preproANP protein corresponding to amino acids: GQTRANPMYNAVSNADLMDFKNLLDHLEEKMPLEDEVVPPQVLSEPNEEAGAALSPLPEVPPWT

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for preproANP Antibody

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105] - Staining of human skeletal muscle shows low expression as expected.
Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105] - Staining of human heart muscle shows high expression.
Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105]

Immunohistochemistry-Paraffin: preproANP Antibody [NBP2-34105] - Staining in human heart muscle and skeletal muscle tissues using anti-preproANP antibody. Corresponding preproANP RNA-seq data are presented for the same tissues.

Applications for preproANP Antibody

Application
Recommended Usage

Immunohistochemistry

1:5000 - 1:10000

Immunohistochemistry-Paraffin

1:5000 - 1:10000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: preproANP

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.

Alternate Names

ANF, ANP, ATFB6, atrial natriuretic factor prohormone, atrial natriuretic peptide prohormone, ATRST2, CDD, CDD-ANF, CDP, natriuretic peptides A, PND

Gene Symbol

NPPA

UniProt

P01160

Additional preproANP Products

Product Documents for preproANP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for preproANP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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