PRKRIR Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-1555

Novus Biologicals, part of Bio-Techne
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NB100-1555
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human, Mouse

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all PRKRIR Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residues 150 and 200 of human Protein-Kinase, Interferon-inducible double strand RNA dependent Inhibitor, Repressor of (P58 Repressor) using the numbering given in entry NP_004696.2 (GeneI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PRKRIR Antibody

Western Blot: PRKRIR Antibody [NB100-1555]

Western Blot: PRKRIR Antibody [NB100-1555]

Western Blot: PRKRIR Antibody [NB100-1555] - Detection of PRKRIR on HeLa whole cell lysate. PRKRIR was also immunoprecipitated using rabbit anti-PRKRIR antibody NB100-1554.
Immunohistochemistry: PRKRIR Antibody [NB100-1555]

Immunohistochemistry: PRKRIR Antibody [NB100-1555]

Immunohistochemistry: PRKRIR Antibody [NB100-1555] - Sample: FFPE sections of human ovarian carcinoma (left) and mouse squamous cell carcinoma (right). Antibody: Affinity purified rabbit anti- PRKRIR used at a dilution of 1:1,000 (0.2ug/ml) and 1:200 (1ug/ml). Detection: DAB
Immunohistochemistry-Paraffin: PRKRIR Antibody [NB100-1555]

Immunohistochemistry-Paraffin: PRKRIR Antibody [NB100-1555]

Immunohistochemistry-Paraffin: PRKRIR Antibody [NB100-1555] - FFPE section of human skin basal cell carcinoma. Affinity purified rabbit anti-PRKRIR used at a dilution of 1:250.
View 1 more images

Applications for PRKRIR Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

1-4 ug/mg of lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: PRKRIR

P58IPK is an inhibitor of the serine/threonine protein kinase, PKR. P58IPK functions to repress eukaryotic initiation factor 2-alpha subunit (eIF-2alpha) phosphorylation by PKR. PRKRIR, also designated P52RIPK, is a P58IPK interacting protein that abrogates P58IPK mediated suppression of PKR activity. PRKRIR is also known as 52 kDa repressor of the inhibitor of the protein kinase, p58IPK-interacting protein, 58 kDa interferon-induced protein kinase-interacting protein, P52rIPK, death-associated protein 4, THAP domain-containing protein 0, and MGC102750.

Alternate Names

58 kDa interferon-induced protein kinase-interacting protein, DAP452 kDa repressor of the inhibitor of the protein kinase, Death-associated protein 4, inhibitor of protein kinase PKR, MGC102750, p52rIPK, p58IPK-interacting protein, protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor), THAP domain-containing protein 0, THAP0

Entrez Gene IDs

5612 (Human); 72981 (Mouse)

Gene Symbol

THAP12

UniProt

NP_004696.2 (Human)

Additional PRKRIR Products

Product Documents for PRKRIR Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PRKRIR Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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