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PRL-2/PTP4A2 Antibody (SR2538)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-27804

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-27804

Key Product Details

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2538

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthetic peptide of human PRL-2/PTP4A2 (Uniprot #: Q12974)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

19 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PRL-2/PTP4A2 Antibody (SR2538)

PRL-2/PTP4A2 Antibody (SR2538)

Western Blot: PRL-2/PTP4A2 Antibody (SR2538) [NBP3-27804] -

Western Blot: PRL-2/PTP4A2 Antibody (SR2538) [NBP3-27804] - Western blot analysis of Hela, A549, HL-60 lysates

Applications for PRL-2/PTP4A2 Antibody (SR2538)

Application
Recommended Usage

Immunoprecipitation

1:20

Western Blot

1:500-1:1000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PRL-2/PTP4A2

PTP4A2 is encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants that encode two distinct isoforms have been described. [provided by RefSeq]

Long Name

Phosphatase of Regenerating Liver 2

Alternate Names

HH13, HH7-2, HU-PP-1, OV-1, PRL2, PTP4A2, PTPCAAX2

Gene Symbol

PTP4A2

Additional PRL-2/PTP4A2 Products

Product Documents for PRL-2/PTP4A2 Antibody (SR2538)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PRL-2/PTP4A2 Antibody (SR2538)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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