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PRODH Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27548

Novus Biologicals, part of Bio-Techne
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NBP2-27548

Key Product Details

Species Reactivity

Human

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

Product Specifications

Immunogen

Peptide with sequence C-EDQESIQPLLRHYR corresponding to internal region according to NP_057419.4, NP_001182155.1.

Specificity

This antibody is expected to recognize both reported isoforms (NP_057419.4; NP_001182155.1).

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for PRODH Antibody

Western Blot: PRODH Antibody [NBP2-27548]

Western Blot: PRODH Antibody [NBP2-27548]

Western Blot: PRODH Antibody [NBP2-27548] - (0.3 ug/ml) Analysis of Human Cerebellum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for PRODH Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

0.3-1 ug/ml
Application Notes
WB: Approx. 75+55 kDa band bands observed in human brain (cerebellum and substantia nigra) lysates (calculated MW of 68.0 kDa kDa band according to NP_057419.4 and of 56.2 kDa band according to NP_001182155.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PRODH

The protein encoded by the PRODH gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome. (provided by RefSeq)

Alternate Names

EC 1.5.99.8, FLJ33744, HSPOX2, mitochondrial, p53-induced gene 6 protein, PIG6MGC148078, POX2, PRODH2MGC148079, proline dehydrogenase (oxidase) 1, proline dehydrogenase (proline oxidase ), Proline oxidase, proline oxidase, mitochondrial, SCZD4, tumor protein p53 inducible protein 6

Gene Symbol

PRODH

Additional PRODH Products

Product Documents for PRODH Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PRODH Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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