Prodynorphin/PDYN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31768

Novus Biologicals, part of Bio-Techne
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NBP1-31768
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Rhesus Macaque (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Prodynorphin/PDYN Antibodies »

Product Specifications

Immunogen

Recombinant protein encompassing a sequence within the center region of human Prodynorphin/PDYN. The exact sequence is proprietary.

Localization

Secreted

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

28 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Prodynorphin/PDYN Antibody

Western Blot: Prodynorphin/PDYN Antibody [NBP1-31768]

Western Blot: Prodynorphin/PDYN Antibody [NBP1-31768]

Western Blot: Prodynorphin/PDYN Antibody [NBP1-31768] - Various tissue extracts (50 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with Prodynorphin/PDYN antibody [N1C2] diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody was used to detect the primary antibody.
Immunohistochemistry-Frozen: Prodynorphin/PDYN Antibody [NBP1-31768]

Immunohistochemistry-Frozen: Prodynorphin/PDYN Antibody [NBP1-31768]

Immunohistochemistry-Frozen: Prodynorphin/PDYN Antibody [NBP1-31768] - Prodynorphin/PDYN antibody [N1C2] detects PDYN protein by immunohistochemical analysis. Sample: Frozen-sectioned mouse hippocampus. Green: Prodynorphin/PDYN stained by Prodynorphin/PDYN antibody [N1C2] diluted at 1:250. Blue: Fluoroshield with DAPI.
Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP1-31768]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP1-31768]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP1-31768] - Human colon carcinoma, using Prodynorphin/PDYN antibody at 1:250 dilution. Antigen Retrieval: Trilogy(TM) (EDTA based, pH 8.0) buffer, 15min.
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Applications for Prodynorphin/PDYN Antibody

Application
Recommended Usage

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Frozen

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Prodynorphin/PDYN

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

Alternate Names

ADCA, Beta-neoendorphin-dynorphin, leu-enkephalin, leumorphin, neoendorphin-dynorphin-enkephalin prepropeptide, PENKB, preprodynorphin, preproenkephalin B, proenkephalin-B, rimorphin, SCA23

Gene Symbol

PDYN

UniProt

P01213 (Human)

Additional Prodynorphin/PDYN Products

Product Documents for Prodynorphin/PDYN Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Prodynorphin/PDYN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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