Prodynorphin/PDYN Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-49081

Novus Biologicals, part of Bio-Techne
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NBP2-49081
NBP2-49081-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Prodynorphin/PDYN Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: SLCAVKTQDGPKPINPLICSLQCQAALLPSEEWERCQSFLSFFTPSTLGLNDKEDLGSKSVGEGPYSELAKLSGSFLKELEKSKFLPSISTKE

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Prodynorphin/PDYN Antibody

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081] - Analysis in human cerebral cortex and liver tissues using NBP2-49081 antibody. Corresponding Prodynorphin/PDYN RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081] - Staining of human cerebral cortex shows moderate granular cytoplasmic positivity in neurons.
Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081]

Immunohistochemistry-Paraffin: Prodynorphin/PDYN Antibody [NBP2-49081] - Staining of human kidney shows no positivity in cells in tubules as expected.
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Applications for Prodynorphin/PDYN Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Prodynorphin/PDYN

The protein encoded by this gene is a preproprotein that is proteolytically processed to form the secreted opioid peptides beta-neoendorphin, dynorphin, leu-enkephalin, rimorphin, and leumorphin. These peptides are ligands for the kappa-type of opioid receptor. Dynorphin is involved in modulating responses to several psychoactive substances, including cocaine. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

Alternate Names

ADCA, Beta-neoendorphin-dynorphin, leu-enkephalin, leumorphin, neoendorphin-dynorphin-enkephalin prepropeptide, PENKB, preprodynorphin, preproenkephalin B, proenkephalin-B, rimorphin, SCA23

Gene Symbol

PDYN

UniProt

P01213 (Human)

Additional Prodynorphin/PDYN Products

Product Documents for Prodynorphin/PDYN Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Prodynorphin/PDYN Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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