Profilin 1 Antibody (S06-6H7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19483

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19483-100ul
NBP3-19483-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-6H7

Concentration

0.3 mg/ml

View all Profilin 1 Antibodies »

Product Summary for Profilin 1 Antibody (S06-6H7)

Immunogen

A synthetic peptide of human Profilin 1 (Uniprot # P07737)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

15 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Profilin 1 Antibody (S06-6H7)

Western Blot: Profilin 1 Antibody (S06-6H7) [NBP3-19483]

Western Blot: Profilin 1 Antibody (S06-6H7) [NBP3-19483]

Western Blot: Profilin 1 Antibody (S06-6H7) [NBP3-19483] - Western blot detection of Profilin 1 in C6, 3T3, Hela cell lysates using NBP3-19483 (1:1000 diluted). Predicted band size: 15kDa. Observed band size: 15kDa.
Immunohistochemistry-Paraffin: Profilin 1 Antibody (S06-6H7) [NBP3-19483]

Immunohistochemistry-Paraffin: Profilin 1 Antibody (S06-6H7) [NBP3-19483]

Immunohistochemistry-Paraffin: Profilin 1 Antibody (S06-6H7) [NBP3-19483] - Immunohistochemistry of Profilin 1 in paraffin-embedded Human tonsil using NBP3-19483 at dilution 1/100

Applications for Profilin 1 Antibody (S06-6H7)

Application
Recommended Usage

Immunohistochemistry

1/50

Western Blot

1/2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Profilin 1

Profilin is an ubiquitous small (12-15 kDa) phosphoinositides and poly-L-proline binding protein that plays a role both in signal transduction pathways and actin filament dynamics. There are two mammalian profilins with similar biochemical properties but different expression patterns. Whereas profilin I appears to be highly expressed in most tissues except for skeletal muscle, profilin II is predominantly expressed in brain and at lower levels. It is also in expressed in skeletal muscle, the uterus and kidneys. Profilin is a mainly cytosolic protein with higher concentrations in dynamic membrane areas like the leading edge and ruffling membranes.

Alternate Names

PFN1, PROF1, Profilin I

Gene Symbol

PFN1

Additional Profilin 1 Products

Product Documents for Profilin 1 Antibody (S06-6H7)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Profilin 1 Antibody (S06-6H7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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