Properdin Antibody (062-27.8.1 (10-18))

Unconjugated

Monoclonal Mouse IgG₁ Clone # 062-27.8.1 (10-18)

1.0 mg/ml

Native purified factor P from human serum

NB100-64749 recognizes human factor P, a 53 kDa glycosylated protein present in blood serum. Factor P binds to microbial surfaces and binds and stabilizes the complement component 3- and complement component 5-convertase enzyme complexes. C3b then acts as an opsonin or initiates the complement pathway again creating a positive feedback loop which acts only on the bacterial cell, leaving the host cells unharmed. Deficiency of factor P makes the host more susceptible to bacterial infections, particularly to Neisseria species and meningococcal infections.

Monoclonal

Mouse

IgG₁

Protein A purified

Borate buffered saline

0.1% Sodium Azide

1.0 mg/ml

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.