Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG_2A

Applications for Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Proprotein Convertase 7/PCSK7

PCSK7 is encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq]

Alternate Names

LPC, PCSK7, SPC7

Gene Symbol

PCSK7

Additional Proprotein Convertase 7/PCSK7 Products

Product Documents for Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Spectra Viewer
Flow Cytometry

Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-73621V

Key Product Details

Species Reactivity

Validated:

Applications

Label

Antibody Source

Concentration

View all Proprotein Convertase 7/PCSK7 Antibodies »

Product Summary for Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

Immunogen

Reactivity Notes

Clonality

Host

Isotype

Applications for Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

Flow Cytometry

Immunocytochemistry/ Immunofluorescence

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: Proprotein Convertase 7/PCSK7

Alternate Names

Gene Symbol

Additional Proprotein Convertase 7/PCSK7 Products

Product Documents for Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for Proprotein Convertase 7/PCSK7 Antibody (OTI1B8) [DyLight 405]

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