Proprotein Convertase 7/PCSK7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00009159-B01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Proprotein Convertase 7/PCSK7 Antibodies »

Product Specifications

Immunogen

PCSK7 (AAH06357.1, 1 a.a. - 591 a.a.) full-length human protein. MPKGRQKVPHLDAPLGLPTCLWLELAGLFLLVPWVMGLAGTGGPDGQGTGGPSWAVHLESLEGDGEEETLEQQADALAQAAGLVNAGRIGELQGHYLFVQPAGHRPALEVEAIRQQVEAVLAGHEAVRWHSEQRLLRRAKRSVHFNDPKYPQQWHLNNRRSPGRDINVTGVWERNVTGRGVTVVVVDDGVEHTIQDIAPNYSPEGSYDLNSNDPDPMPHPDVENGNHHGTRCAGEIAAVPNNSFCAVGVAYGSRIAGIRVLDGPLTDSMEAVAFNKHYQINDIYSCSWGPDDDGKTVDGPHQLGKAALQHGVIAGRQGFGSIFVVASGNGGQHNDNCNYDGYANSIYTVTIGAVDEEGRMPFYAEECASMLAVTFSGGDKMLRSIVTTDWDLQKGTGCTEGHTGTSAAAPLAAGMIALMLQVRPCLTWRDVQHIIVFTATRYEDRRAEWVTNEAGFSHSHQHGFGLLNAWRLVNAAKIWTSVPYLASYVSPVLKENKAIPQSPRSLEVLWNVSRMDLEMSGLKTLEHVAVTVSITHPRRGSLELKLFCPSGMMSLIGAPRSMDSWLCVECSRHQGQTKAVRECHEWKIPAR

Specificity

PCSK7 - proprotein convertase subtilisin/kexin type 7,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for Proprotein Convertase 7/PCSK7 Antibody

Western Blot: Proprotein Convertase 7/PCSK7 Antibody [H00009159-B01P]

Western Blot: Proprotein Convertase 7/PCSK7 Antibody [H00009159-B01P]

Western Blot: Proprotein Convertase 7/PCSK7 Antibody [H00009159-B01P] - Analysis of PCSK7 expression in transfected 293T cell line by PCSK7 polyclonal antibody. Lane 1: PCSK7 transfected lysate(65.01 KDa). Lane 2: Non-transfected lysate.
Western Blot: Proprotein Convertase 7/PCSK7 Antibody [H00009159-B01P]

Western Blot: Proprotein Convertase 7/PCSK7 Antibody [H00009159-B01P]

Western Blot: Proprotein Convertase 7/PCSK7 Antibody [H00009159-B01P] - analysis of PCSK7 expression in transfected 293T cell line by PCSK7 MaxPab polyclonal antibody. Lane 1: PCSK7 transfected lysate (65.01 KDa). Lane 2: Non-transfected lysate.

Applications for Proprotein Convertase 7/PCSK7 Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Proprotein Convertase 7/PCSK7

The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq]

Alternate Names

LPC, PCSK7, SPC7

Entrez Gene IDs

9159 (Human)

Gene Symbol

PCSK7

UniProt

AAH06357.1 (Human)

Additional Proprotein Convertase 7/PCSK7 Products

Product Documents for Proprotein Convertase 7/PCSK7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Proprotein Convertase 7/PCSK7 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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