Proteasome 20S beta 6 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57831

Novus Biologicals, part of Bio-Techne
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NBP2-57831
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Proteasome 20S beta 6 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPM

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Proteasome 20S beta 6 Antibody

Western Blot: Proteasome 20S beta 6 Antibody [NBP2-57831]

Western Blot: Proteasome 20S beta 6 Antibody [NBP2-57831]

Western Blot: Proteasome 20S beta 6 Antibody [NBP2-57831] - Analysis in human cell line A-549.
Immunocytochemistry/ Immunofluorescence: Proteasome 20S beta 6 Antibody [NBP2-57831]

Immunocytochemistry/ Immunofluorescence: Proteasome 20S beta 6 Antibody [NBP2-57831]

Immunocytochemistry/Immunofluorescence: Proteasome 20S beta 6 Antibody [NBP2-57831] - Staining of human cell line PC-3 shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.

Applications for Proteasome 20S beta 6 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Proteasome 20S beta 6

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 1i (proteasome beta 9 subunit).

Long Name

Proteasome subunit beta type-6

Alternate Names

EC 3.4.25.1, LMPY, PSMB6

Gene Symbol

PSMB6

Additional Proteasome 20S beta 6 Products

Product Documents for Proteasome 20S beta 6 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Proteasome 20S beta 6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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