Protein Phosphatase 1C gamma Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-75543

Novus Biologicals, part of Bio-Techne
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NB100-75543
NB100-75543-0.025mg
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Bovine

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Chicken

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Protein Phosphatase 1C gamma Antibodies »

Product Summary for Protein Phosphatase 1C gamma Antibody

Immunogen

The immunogen for this antibody was a sequence from 1a.a. to 323a.a. from PP1C(a 323a.a. long protein)

Reactivity Notes

This antibody is reactive against Human, mouse, rat, bovine.

Localization

Cytoplasmic

Specificity

Protein Phosphatase 1C gamma

Clonality

Polyclonal

Host

Chicken

Applications for Protein Phosphatase 1C gamma Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Western Blot: E coli-derived recombinant protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2)

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Protein Phosphatase 1C gamma

Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. The protein is involved in regulation of ionic conductances and long term synaptic plasticity. It may play an important role in dephosphorylating substrates such as the postsynaptic density associated Ca (2+)/calmodulin dependent protein kinase II. PP1 comprises a catalytic subunit, PPP1CA, PPP1CB or PPP1CC (PP1C gamma), which is folded into its native form by inhibitor 2 and glycogen synthetase kinase 3, and then complexed to one or several targeting or regulatory subunits. PPP1R12A and PPP1R12B mediate binding to myosin. PPP1R3A, PPP1R3B, PPP1R3C and PPP1R3D mediate binding to glycogen. Interacts with cyanobacterial toxin microcystin; disulfide-linked. Interacts with PPP1R7.

Alternate Names

EC 3.1.3.16, PP-1G, PP1gamma, PPP1G, protein phosphatase 1, catalytic subunit, gamma isoform, protein phosphatase 1, catalytic subunit, gamma isozyme, Protein phosphatase 1C catalytic subunit, serine/threonine phosphatase 1 gamma, serine/threonine-protein phosphatase PP1-gamma catalytic subunit

Entrez Gene IDs

5501 (Human); 19047 (Mouse); 24669 (Rat)

Gene Symbol

PPP1CC

UniProt

P36873 (Human)

Additional Protein Phosphatase 1C gamma Products

Product Documents for Protein Phosphatase 1C gamma Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Protein Phosphatase 1C gamma Antibody

Chicken products cannot be exported to Canada.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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