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Protocadherin beta 3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-15063

Novus Biologicals, part of Bio-Techne
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NBP2-15063

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Primate (99%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Protocadherin beta 3 Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Protocadherin beta 3. The exact sequence is proprietary.

Reactivity Notes

Chimpanzee (99%), Rat (81%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

87 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Protocadherin beta 3 Antibody

Western Blot: Protocadherin beta 3 Antibody [NBP2-15063]

Western Blot: Protocadherin beta 3 Antibody [NBP2-15063]

Western Blot: Protocadherin beta 3 Antibody [NBP2-15063] - Sample (20 ug ) A: Hela cell membrane 7. 5% SDS PAGE; antibody diluted at 1:1000.

Applications for Protocadherin beta 3 Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Protocadherin beta 3

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections. [provided by RefSeq]

Alternate Names

PCDH-BETA3, PCDH-beta-3, protocadherin beta 3, protocadherin beta-3

Gene Symbol

PCDHB3

UniProt

Additional Protocadherin beta 3 Products

Product Documents for Protocadherin beta 3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Protocadherin beta 3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.