PSMA7 Antibody (OTI3F11)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-02120

Novus Biologicals, part of Bio-Techne
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NBP2-02120
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3F11

Concentration

0.66 mg/ml

View all PSMA7 Antibodies »

Product Specifications

Immunogen

Full length human recombinant protein of human PSMA7 (NP_002783) produced in HEK293T cell.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Mouse-On-Mouse blocking reagent may be needed for IHC and ICC experiments to reduce high background signal. You can find these reagents under catalog numbers PK-2200-NB and MP-2400-NB. Please contact Technical Support if you have any questions.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

27.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PSMA7 Antibody (OTI3F11)

Western Blot: PSMA7 Antibody (OTI3F11) [NBP2-02120]

Western Blot: PSMA7 Antibody (OTI3F11) [NBP2-02120]

Western Blot: PSMA7 Antibody (3F11) [NBP2-02120] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PSMA7 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PSMA7.
Immunohistochemistry-Paraffin: PSMA7 Antibody (3F11) [NBP2-02120] Staining of paraffin-embedded thyroid tissue using anti-PSMA7mouse monoclonal antibody.
Flow Cytometry: PSMA7 Antibody (OTI3F11) [NBP2-02120]

Flow Cytometry: PSMA7 Antibody (OTI3F11) [NBP2-02120]

Flow Cytometry: PSMA7 Antibody (3F11) [NBP2-02120] - HEK293T cells transfected with either pCMV6-ENTRY PSMA7.(Red) or empty vector control plasmid (Blue) were immunostained with anti-PSMA7 mouse monoclonal, and then analyzed by flow cytometry.
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Applications for PSMA7 Antibody (OTI3F11)

Application
Recommended Usage

Flow Cytometry

1:100

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:50

Western Blot

1:2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

0.66 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PSMA7

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension. Multiple isoforms of this subunit arising from alternative splicing may exist but alternative transcripts for only two isoforms have been defined. A pseudogene has been identified on chromosome 9.

Long Name

Proteasome subunit alpha type-7

Alternate Names

HSPC

Entrez Gene IDs

5688 (Human)

Gene Symbol

PSMA7

Additional PSMA7 Products

Product Documents for PSMA7 Antibody (OTI3F11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PSMA7 Antibody (OTI3F11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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