PSTPIP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25078

Novus Biologicals, part of Bio-Techne
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NBP3-25078
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PSTPIP1 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein PSTPIP1 using the following amino acid sequence: LTILRNALWVHSNQLSMQCVKDDELYEEVRLTLEGCSIDADIDSFIQAKSTGTEPPAPVPYQNYYDREVTPLTSSPGIQPSC

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PSTPIP1 Antibody

PSTPIP1 Antibody Western Blot: PSTPIP1 Antibody [NBP3-25078]

Western Blot: PSTPIP1 Antibody [NBP3-25078]

Analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue.
PSTPIP1 Antibody Immunohistochemistry-Paraffin: PSTPIP1 Antibody [NBP3-25078]

Immunohistochemistry-Paraffin: PSTPIP1 Antibody [NBP3-25078]

Staining of human bone marrow shows moderate cytoplasmic positivity in hematopoietic cells.

Applications for PSTPIP1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 µg/ml
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PSTPIP1

The protein encoded by the PSTPIP1 gene binds to the cytoplasmic tail of CD2, an effector of T cell activation and adhesion, negatively affecting CD2-triggered T cell activation. The encoded protein appears to be a scaffold protein and a regulator of the actin cytoskeleton. It has also been shown to bind ABL1, PTPN18, WAS, CD2AP, and PTPN12. Mutations in this gene are a cause of PAPA syndrome. (provided by RefSeq)

Alternate Names

CD2BP1CD2-binding protein 1, CD2BP1L, CD2BP1S, H-PIPPEST phosphatase-interacting protein 1, PAPASCD2 antigen-binding protein 1, proline-serine-threonine phosphatase interacting protein 1, proline-serine-threonine phosphatase-interacting protein 1, PSTPIPCD2 cytoplasmic tail-binding protein

Gene Symbol

PSTPIP1

Additional PSTPIP1 Products

Product Documents for PSTPIP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PSTPIP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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