PTENP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00011191-B01P

Novus Biologicals, part of Bio-Techne
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H00011191-B01P
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Mouse IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PTENP1 Antibodies »

Product Specifications

Immunogen

PTENP1 (AAH38293.1, 1 a.a. - 369 a.a.) full-length human protein. MGFPAERLEGVYRNNIDDVVRFLDSKHKNHYKIHNLCAERHYDTAKSNYRVAQYPFEDHNPPQLELIKPFCEDLDQWLSEDDNHVAAIHCKAGKGRTGIMIYAYLLHRGKFLKAQEALDFYGEVRTRDKKGVTIPSQRRYVYYYSYLVKNHVDYRPVALLFHKMMFETIPMFSGGTCNPQFVVCQLKVKMYSSNSGPTRWEDKFMYFEFPQPLPVCGGIKVEFFHKQNKMLKKDKMFHFWVNTFFIPGPEETSEKVENGSLCDQEIDSICSIERADNDKEYLVLTLTKNDLDKANKDKANRYFSPNFKVKLYFTKTVEEPSNPEASSSTSVTPDVSDNEPDHYRYSDTTDSDPENEPFDEDQHTQITKV

Specificity

PTENP1 - phosphatase and tensin homolog (mutated in multiple advanced cancers 1), pseudogene 1,

Clonality

Polyclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for PTENP1 Antibody

Western Blot: PTENP1 Antibody [H00011191-B01P]

Western Blot: PTENP1 Antibody [H00011191-B01P]

Western Blot: PTENP1 Antibody [H00011191-B01P] - Analysis of PTENP1 expression in transfected 293T cell line by PTENP1 polyclonal antibody. Lane 1: PTENP1 transfected lysate(40.59 KDa). Lane 2: Non-transfected lysate.

Applications for PTENP1 Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PTENP1

PTENP1 is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.

Alternate Names

phosphatase and tensin homolog pseudogene 1, psiPTEN, PTEN2, PTH2, PTEN-rs

Entrez Gene IDs

11191 (Human)

Gene Symbol

PTENP1

Additional PTENP1 Products

Product Documents for PTENP1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PTENP1 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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