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PTGER4/EP4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00005734-D01P

Novus Biologicals, part of Bio-Techne
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H00005734-D01P

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

PTGER4 (NP_000949.1, 1 a.a. - 488 a.a.) full-length human protein. MSTPGVNSSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKETTFYTLVCGLAVTDLLGTLLVSPVTIATYMKGQWPGGQPLCEYSTFILLFFSLSGLSIICAMSVERYLAINHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAHAAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGHPAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQPSLEREVSKNPDLQAIRIASVNPILDPWIYILLRKTVLSKAIEKIKCLFCRIGGSRRERSGQHCSDSQRTSSAMSGHSRSFISRELKEISSTSQTLLPDLSLPDLSENGLGGRNLLPGVPGMGLAQEDTTSLRTLRISETSDSSQGQDSESVLLVDEAGGSGRAGPAPKGSSLQVTFPSETLNLSEKCI

Specificity

Reacts with prostaglandin E receptor 4 (subtype EP4).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for PTGER4/EP4 Antibody

Western Blot: PTGER4/EP4 Antibody [H00005734-D01P]

Western Blot: PTGER4/EP4 Antibody [H00005734-D01P]

Western Blot: PTGER4/EP4 Antibody [H00005734-D01P] - Analysis of PTGER4 expression in Jurkat.
Western Blot: PTGER4/EP4 Antibody [H00005734-D01P]

Western Blot: PTGER4/EP4 Antibody [H00005734-D01P]

Western Blot: PTGER4/EP4 Antibody [H00005734-D01P] - Analysis of PTGER4 expression in transfected 293T cell line by PTGER4 polyclonal antibody.Lane 1: PTGER4 transfected lysate(53.10 KDa).Lane 2: Non-transfected lysate.

Applications for PTGER4/EP4 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against cell and transfected lysate in WB and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PTGER4/EP4

The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq]

Long Name

Prostaglandin E2 Receptor 4, Subtype EP4

Alternate Names

EP4, EP4R

Entrez Gene IDs

5734 (Human)

Gene Symbol

PTGER4

Additional PTGER4/EP4 Products

Product Documents for PTGER4/EP4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTGER4/EP4 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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