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PTGER4/EP4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NLS3898

Novus Biologicals, part of Bio-Techne
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NLS3898

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Cited:

Human, Mouse

Predicted:

Chimpanzee (93%), Primate (93%). Backed by our 100% Guarantee.

Applications

Validated:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Synthetic 14 amino acid peptide from N-terminal extracellular domain of human PTGER4/EP4.

Epitope

N-terminal extracellular domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (93%), Marmoset (93%), Gibbon (86%), Monkey (86%). Mouse reactivity reported in (PMID: 21600299).

Specificity

Human PTGER4/EP4. BLAST analysis of the peptide immunogen showed no homology with other human proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTGER4/EP4 Antibody

Immunocytochemistry/ Immunofluorescence: PTGER4/EP4 Antibody [NLS3898]

Immunocytochemistry/ Immunofluorescence: PTGER4/EP4 Antibody [NLS3898]

Immunocytochemistry/Immunofluorescence: PTGER4/EP4 Antibody [NLS3898] - Analysis of anti-PTGER4 / EP4 antibody with transfected cells expressing Prostaglandin E Receptor EP4 at 8 ug/ml.
Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3898]

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3898]

Immunohistochemistry-Paraffin: PTGER4/EP4 Antibody [NLS3898] - Analysis of anti-PTGER4 / EP4 antibody with human colon, ganglion 8 ug/ml.
Immunocytochemistry/ Immunofluorescence: PTGER4/EP4 Antibody [NLS3898]

Immunocytochemistry/ Immunofluorescence: PTGER4/EP4 Antibody [NLS3898]

Immunocytochemistry/Immunofluorescence: PTGER4/EP4 Antibody [NLS3898] - Analysis of anti-PTGER4 / EP4 antibody with transfection control.

Applications for PTGER4/EP4 Antibody

Application
Recommended Usage

Immunohistochemistry

10-20 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml
Application Notes
Use in FLOW reported in scientific literature (PMID: 25218986). Use in WB reported in scientific literature (PMID: 21600299). .

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTGER4/EP4

Prostaglandin E receptor EP4 is a Prostanoid Receptor with a relaxing effect on smooth muscle. It may play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. EP4 has been reported to be expressed in blood, colon, immune tissue, intestine, kidney, lung, ovary, skin, and uterus. ESTs have been isolated from a wide range of human tissue libraries.

Long Name

Prostaglandin E2 Receptor 4, Subtype EP4

Alternate Names

EP4, EP4R

Entrez Gene IDs

5734 (Human)

Gene Symbol

PTGER4

Additional PTGER4/EP4 Products

Product Documents for PTGER4/EP4 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTGER4/EP4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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