PTH1R/PTHR1 Antibody (SR2114)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21942

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-21942-50ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR2114

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all PTH1R/PTHR1 Antibodies »

Product Summary for PTH1R/PTHR1 Antibody (SR2114)

Immunogen

A synthesized peptide derived from human PTH1R/PTHR1 (Uniprot #: Q03431)

Specificity

Detects endogenous levels of total PTH1R/PTHR1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

66 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PTH1R/PTHR1 Antibody (SR2114)

Western Blot: PTH1R/PTHR1 Antibody (SR2114) [NBP3-21942] -

Western Blot: PTH1R/PTHR1 Antibody (SR2114) [NBP3-21942] - Western blot analysis using NBP3-21942 in HeLa cell lysate.

Applications for PTH1R/PTHR1 Antibody (SR2114)

Application
Recommended Usage

Immunoprecipitation

1:50

Western Blot

1:500-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTH1R/PTHR1

PTHR1, a Parathyroid Hormone Receptor, mediates PTH-dependent regulation of mineral-ion homeostasis. It also mediates the paracrine action of PTHRP in endochondral bone formation. Mutations in this receptor are responsible for disorders of calcium and bone metabolism such as chondrodysplasia, hypercalcemia, and chronic renal failure. Three promoters, P1, P2, and P3, regulate the expression of PTHR. PTHR1 has been reported to be expressed in bone, breast, brain, colon, GI, kidney, liver, placenta, skin, umbilical cord, and uterus. ESTs have been isolated from B-cell/lung/testis, brain, breast, fetus, heart, heart/melanocyte/uterus, kidney, liver/spleen, lung, placenta, and testis libraries.

Long Name

Parathyroid Hormone Receptor 1

Alternate Names

PTHR, PTHR1

Gene Symbol

PTH1R

Additional PTH1R/PTHR1 Products

Product Documents for PTH1R/PTHR1 Antibody (SR2114)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PTH1R/PTHR1 Antibody (SR2114)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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