PTIP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88233

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-88233
NBP1-88233-25ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PTIP Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EEEEEVENEEQDSQNEGSTDEKSSPASSQEGSPSGDQQFSPKSNTEKSKGELMFDDSSDSSPEKQERNLNWTPAEVPQLAAAKRRLPQGKEPGLINLCANVPPVPGNILPPEVRGNLMAAGQNLQSSERS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTIP Antibody

Western Blot: PTIP Antibody [NBP1-88233]

Western Blot: PTIP Antibody [NBP1-88233]

Western Blot: PTIP Antibody [NBP1-88233] - Staining of human liver shows low expression as expected.
Immunohistochemistry-Paraffin: PTIP Antibody [NBP1-88233]

Immunohistochemistry-Paraffin: PTIP Antibody [NBP1-88233]

Immunohistochemistry-Paraffin: PTIP Antibody [NBP1-88233] - Staining of human testis shows high expression.
Western Blot: PTIP Antibody [NBP1-88233]

Western Blot: PTIP Antibody [NBP1-88233]

Western Blot: PTIP Antibody [NBP1-88233] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted)
View 2 more images

Applications for PTIP Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTIP

PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. Tandem BRCT (BRCA1 carboxyl-terminal) domains in PTIP and in BRCA1 serve as phosphoserine or phosphothreonine specific binding modules that recognize substrates phosphorylated by the kinases ATM and ATR in response to gamma irradiation.

Alternate Names

CAGF28, PACIP1, PAX interacting (with transcription-activation domain) protein 1, PAX transactivation activation domain-interacting protein, PAX transcription activation domain interacting protein 1 like, PAX-interacting protein 1, PAXIP1LCAGF29, protein encoded by CAG trinucleotide repeats, PTIPFLJ41049, TNRC2

Gene Symbol

PAXIP1

Additional PTIP Products

Product Documents for PTIP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for PTIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.