PTP pi/PTPRU Antibody (PTPRU/7616)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-23865

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 kappa Clone # PTPRU/7616

Concentration

0.2 mg/ml

View all PTP pi/PTPRU Antibodies »

Product Summary for PTP pi/PTPRU Antibody (PTPRU/7616)

Immunogen

Recombinant fragment (around aa1-200) of human PTP pi/PTPRU protein (exact sequence is proprietary)

Localization

Cell junction. Cell membrane. Single-pass type I membrane protein.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2 kappa

Description

Store at 2 to 8C. Non-hazardous. No MSDS required.

Scientific Data Images for PTP pi/PTPRU Antibody (PTPRU/7616)

PTP pi/PTPRU Antibody (PTPRU/7616)

Immunohistochemistry-Paraffin: PTP pi/PTPRU Antibody (PTPRU/7616) [NBP3-23865] -

Formalin-fixed, paraffin-embedded human prostate stained with PTP pi/PTPRU antibody (PTPRU/7616). HIER: Tris/EDTA, pH9.0, 45min. Secondary: HRP-polymer, 30min. DAB, 5min.

Applications for PTP pi/PTPRU Antibody (PTPRU/7616)

Application
Recommended Usage

Immunohistochemistry-Paraffin

1-2ug/ml
Application Notes
Immunohistochemistry-Paraffin: 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes. Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: PTP pi/PTPRU

The protein encoded by the PTPRU gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Three alternatively spliced transcript variants, which encode distinct proteins, have been reported. (provided by RefSeq)

Long Name

Receptor-type Protein Tyrosine Phosphatase pi

Alternate Names

FMI, GLEPP1, PCP-2, pi R-PTP-Psi, PTP-J, PTP-PI, PTPRO, PTPRU, R-PTP-U

Gene Symbol

PTPRU

Additional PTP pi/PTPRU Products

Product Documents for PTP pi/PTPRU Antibody (PTPRU/7616)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PTP pi/PTPRU Antibody (PTPRU/7616)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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