PTP4A1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-93524

Novus Biologicals, part of Bio-Techne
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NB100-93524
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all PRL-1/PTP4A1 Antibodies »

Product Specifications

Immunogen

Peptide with sequence KDSNGHRNNCCIQ corresponding to C-Terminus according to NP_003454.1.

Epitope

KDSNGHRNNCCIQ

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for PTP4A1 Antibody

Western Blot: PTP4A1 Antibody [NB100-93524]

Western Blot: PTP4A1 Antibody [NB100-93524]

Western Blot: PTP4A1 Antibody [NB100-93524] - (1ug/ml) staining of A549 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for PTP4A1 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:2000

Western Blot

1 - 3 ug/ml
Application Notes
WB: Approx. 21 kDa band observed in A549 and HeLa lysates (calculated MW of 19.8 kDa band according to NP_003454.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: PRL-1/PTP4A1

The protein encoded by this gene belongs to a small class of prenylated protein tyrosine phosphatases (PTPs), which contains a PTP domain and a characteristic C-terminal prenylation motif. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This tyrosine phosphatase is a nuclear protein, but may primarily associate with plasma membrane. The surface membrane association of this protein depends on its C-terminal prenylation. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which implicated its role in the tumorigenesis. Studies in rat suggested that this gene may be an immediate-early gene in mitogen-stimulated cells. [provided by RefSeq]

Long Name

Phosphatase of Regenerating Liver 1

Alternate Names

HH72, PRL1, PTP(CAAX1)

Entrez Gene IDs

7803 (Human)

Gene Symbol

PTP4A1

UniProt

NP_003454.1 (Human)

Additional PRL-1/PTP4A1 Products

Product Documents for PTP4A1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PTP4A1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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