PTPN7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00005778-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Proximity Ligation Assay, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PTPN7 Antibodies »

Product Specifications

Immunogen

PTPN7 (NP_002823.2, 1 a.a. - 360 a.a.) full-length human protein. MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP

Specificity

PTPN7,

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Quality control test: Antibody reactive against mammalian transfected lysate.

Scientific Data Images for PTPN7 Antibody

Western Blot: PTPN7 Antibody [H00005778-D01P]

Western Blot: PTPN7 Antibody [H00005778-D01P]

Western Blot: PTPN7 Antibody [H00005778-D01P] - Analysis of PTPN7 expression in transfected 293T cell line by PTPN7 polyclonal antibody.Lane 1: PTPN7 transfected lysate(40.50 KDa).Lane 2: Non-transfected lysate.
Proximity Ligation Assay: PTPN7 Antibody [H00005778-D01P]

Proximity Ligation Assay: PTPN7 Antibody [H00005778-D01P]

Proximity Ligation Assay: PTPN7 Antibody [H00005778-D01P] - Analysis of protein-protein interactions between PTPN7 and MAPK1. HeLa cells were stained with anti-PTPN7 rabbit purified polyclonal 1:1200 and anti-MAPK1 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Applications for PTPN7 Antibody

Application
Recommended Usage

Proximity Ligation Assay

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
It has been used for ELISA and WB.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: PTPN7

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Tyrosine-protein phosphatase non-receptor type 7

Alternate Names

BPTP-4, FLJ18703, HEPTPnonreceptor-type, stress induced, LPTP, protein tyrosine phosphatase, non-receptor type 7, tyrosine-protein phosphatase non-receptor type 7

Entrez Gene IDs

5778 (Human)

Gene Symbol

PTPN7

UniProt

NP_002823.2 (Human)

Additional PTPN7 Products

Product Documents for PTPN7 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PTPN7 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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