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PTPN7 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81756

Novus Biologicals, part of Bio-Techne
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NBP1-81756
NBP1-81756-25ul

Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (93%), Rat (92%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for PTPN7 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQL

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTPN7 Antibody

Immunohistochemistry-Paraffin: PTPN7 Antibody [NBP1-81756]

Immunohistochemistry-Paraffin: PTPN7 Antibody [NBP1-81756]

Immunohistochemistry-Paraffin: PTPN7 Antibody [NBP1-81756] - (PTPN7) at 1:100, using EDTA pre-treatment, on WHO grade I and II meningioma paraffin slides. Image from verified customer review.
Immunohistochemistry-Paraffin: PTPN7 Antibody [NBP1-81756]

Immunohistochemistry-Paraffin: PTPN7 Antibody [NBP1-81756]

Immunohistochemistry-Paraffin: PTPN7 Antibody [NBP1-81756] - Staining of human tonsil shows strong cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra.

Applications for PTPN7 Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 5 using NBP1-81756 in the following applications:

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTPN7

PTPN7 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The noncatalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Long Name

Tyrosine-protein phosphatase non-receptor type 7

Alternate Names

BPTP-4, FLJ18703, HEPTPnonreceptor-type, stress induced, LPTP, protein tyrosine phosphatase, non-receptor type 7, tyrosine-protein phosphatase non-receptor type 7

Gene Symbol

PTPN7

Additional PTPN7 Products

Product Documents for PTPN7 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTPN7 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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