PTPRN2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81628

Novus Biologicals, part of Bio-Techne
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NBP1-81628
NBP1-81628-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all PTPRN2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: QDDDDRLYQEVHRLSATLGGLLQDHGSRLLPGALPFARPLDMERKKSEHPESSLSSEEETAGVENVKSQTYSKDLLGQQPHSEPGAAAFGELQNQMPGPSKEEQSLPAGAQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTPRN2 Antibody

Western Blot: PTPRN2 Antibody [NBP1-81628]

Western Blot: PTPRN2 Antibody [NBP1-81628]

Western Blot: PTPRN2 Antibody [NBP1-81628] - Analysis in human cell line U-87 MG.
Immunocytochemistry/ Immunofluorescence: PTPRN2 Antibody [NBP1-81628]

Immunocytochemistry/ Immunofluorescence: PTPRN2 Antibody [NBP1-81628]

Immunocytochemistry/Immunofluorescence: PTPRN2 Antibody [NBP1-81628] - Staining of human cell line AF22 shows localization to vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: PTPRN2 Antibody [NBP1-81628]

Immunohistochemistry-Paraffin: PTPRN2 Antibody [NBP1-81628]

Immunohistochemistry-Paraffin: PTPRN2 Antibody [NBP1-81628] - Staining of human liver shows strong cytoplasmic positivity in bile duct cells.

Applications for PTPRN2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation/Permeabilization: PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTPRN2

PTPRN2 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. The catalytic domain of this PTP is most closely related to PTPRN/IA-2beta. This PTP and PTPRN are both found to be major autoantigens associated with insulin-dependent diabetes mellitus. Three alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported.

Alternate Names

EC 3.1.3.48, IA-2beta, IAR/receptor-like protein-tyrosine phosphatase, ICAARIARPTPRP, Islet cell autoantigen-related protein, KIAA0387, phogrin, protein tyrosine phosphatase receptor pi, protein tyrosine phosphatase, receptor type, N polypeptide 2, receptor-type tyrosine-protein phosphatase N2, R-PTP-N2, tyrosine phosphatase IA-2 beta

Gene Symbol

PTPRN2

Additional PTPRN2 Products

Product Documents for PTPRN2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for PTPRN2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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