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PTPRO Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81826

Novus Biologicals, part of Bio-Techne
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NBP1-81826
NBP1-81826-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

IF/IHC

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: TRVNISYWEGKDFRTMLYKDFFKGKTVFNHWLPGMCYSNITFQLVSEATFNKSTLVEYSGVSHEPKQHRTAPYPPQNISVRIVNLNKNNWEEQSGNFPEESFMRSQDTIGKEKLFHFTEETPEIPSGNISSGWP

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (83%), Rat (84%). Human reactivity reported in scientific literature (PMID: 25826083).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for PTPRO Antibody

Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826]

Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826]

Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining in human kidney and skeletal muscle tissues . Corresponding PTPRO RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826]

Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826]

Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826]

Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826]

Immunohistochemistry-Paraffin: PTPRO Antibody [NBP1-81826] - Staining of human kidney shows strong membranous positivity in cells in glomeruli.

Applications for PTPRO Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
IHC reported in scientific literature (PMID: 25826083). For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTPRO

PTPRO encodes a receptor-type protein tyrosine phosphatase containing a single intracellular catalytic domain with a characteristic signature motif. The gene product, which has a transmembrane domain, is an integral membrane protein. Several alternatively spliced transcript variants, some of which encode different isoforms of the protein, have been described. These variants exhibit tissue-specific expression. [provided by RefSeq]

Alternate Names

EC 3.1.3.48, GLEPP1PTPROt, Glomerular epithelial protein 1, phosphotyrosine phosphatase U2, protein tyrosine phosphatase PTP-U2, Protein tyrosine phosphatase U2, protein tyrosine phosphatase, receptor type, O, PTPase U2, PTP-oc, PTP-U2glomerular epithelial protein-1, PTPU2osteoclastic transmembrane protein-tyrosine phosphatase, receptor-type protein tyrosine phosphatase O, receptor-type tyrosine-protein phosphatase O, R-PTP-O

Gene Symbol

PTPRO

Additional PTPRO Products

Product Documents for PTPRO Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTPRO Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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