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PTS [p Ser19] Antibody (SR1297)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-21604

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
Catalog #
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NBP3-21604-100ul
NBP3-21604-50ul

Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1297

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

A synthesized peptide derived from human phospho-PTS [Ser19] (Uniprot #: Q03393)

Modification

p Ser 19

Specificity

Detects endogenous levels of total phospho-PTS [Ser19]

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

18 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PTS [p Ser19] Antibody (SR1297)

Western Blot: PTS [p Ser 19] Antibody (SR1297) [NBP3-21604] -

Western Blot: PTS [p Ser 19] Antibody (SR1297) [NBP3-21604] - Western blot analysis using NBP3-21604 in (1) HUVEC cell lysate; (2) HUVEC cell treated with Alkaline Phosphatase lysate.

Applications for PTS [p Ser19] Antibody (SR1297)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PTS

The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia. [provided by RefSeq]

Alternate Names

6-pyruvoyl tetrahydrobiopterin synthase, 6-pyruvoyltetrahydropterin synthase, EC 4.2.3.12, FLJ97081, PTPSPTP synthase

Gene Symbol

PTS

Additional PTS Products

Product Documents for PTS [p Ser19] Antibody (SR1297)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PTS [p Ser19] Antibody (SR1297)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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