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PURA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-10969

Novus Biologicals, part of Bio-Techne
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NBP3-10969-100ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

0.5 mg/ml

Product Summary for PURA Antibody

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of human PURA (NP_005850). Peptide sequence VEFRDYLGDFIEHYAQLGPSQPPDLAQAQDEPRRALKSEFLVRENRKYYM

Clonality

Polyclonal

Host

Rabbit

Theoretical MW

35 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for PURA Antibody

Immunohistochemistry: PURA Antibody [NBP3-10969]

Immunohistochemistry: PURA Antibody [NBP3-10969]

Immunohistochemistry: PURA Antibody [NBP3-10969] - Immunohistochemical analysis of cerebellum tissue at an antibody concentration of 5ug/ml

Applications for PURA Antibody

Application
Recommended Usage

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: PURA

PURA product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia.

Alternate Names

PUR1PUR-ALPHA, PURALPHA, purine-rich element binding protein A, Purine-rich single-stranded DNA-binding protein alpha, transcriptional activator protein Pur-alpha

Gene Symbol

PURA

Additional PURA Products

Product Documents for PURA Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for PURA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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