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QPRT Antibody (OTI1C10) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-73761

Novus Biologicals, part of Bio-Techne
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NBP2-73761
Conjugate
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Key Product Details

Species Reactivity

Human

Applications

CyTOF-ready, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI1C10

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

Product Specifications

Immunogen

Full length human recombinant protein of human QPRT (NP_055113) produced in HEK293T cell.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

30.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for QPRT Antibody (OTI1C10) - Azide and BSA Free

Western Blot: QPRT Antibody (OTI1C10)Azide and BSA Free [NBP2-73761]

Western Blot: QPRT Antibody (OTI1C10)Azide and BSA Free [NBP2-73761]

Western Blot: QPRT Antibody (OTI1C10) - Azide and BSA Free [NBP2-73761] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY QPRT (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-QPRT.
Immunocytochemistry/ Immunofluorescence: QPRT Antibody (OTI1C10) - Azide and BSA Free [NBP2-73761]

Immunocytochemistry/ Immunofluorescence: QPRT Antibody (OTI1C10) - Azide and BSA Free [NBP2-73761]

Immunocytochemistry/Immunofluorescence: QPRT Antibody (OTI1C10) - Azide and BSA Free [NBP2-73761] - Staining of COS7 cells transiently transfected by pCMV6-ENTRY QPRT.
Immunohistochemistry: QPRT Antibody (OTI1C10) - Azide and BSA Free [NBP2-73761]

Immunohistochemistry: QPRT Antibody (OTI1C10) - Azide and BSA Free [NBP2-73761]

Immunohistochemistry: QPRT Antibody (OTI1C10) - Azide and BSA Free [NBP2-73761] - Staining of paraffin-embedded Human lymphoma tissue using anti-QPRT mouse monoclonal antibody.

Applications for QPRT Antibody (OTI1C10) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:100

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:150

Western Blot

1:500-2000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Reconstitution

we recommend adding 100uL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiment, we strongly recommend performing another round of desalting process.

Formulation

Lyophilized from PBS (pH 7.3) with 8% Trehalose

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: QPRT

QPRT encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease.

Alternate Names

EC 2.4.2.19, nicotinate-nucleotide pyrophosphorylase (carboxylating), QAPRTase, QPRTasenicotinate-nucleotide pyrophosphorylase [carboxylating], quinolinate phosphoribosyltransferase, Quinolinate phosphoribosyltransferase [decarboxylating]

Gene Symbol

QPRT

Additional QPRT Products

Product Documents for QPRT Antibody (OTI1C10) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for QPRT Antibody (OTI1C10) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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